Lynch Syndrome documents and resources for clinicians

On this page you will find Lynch Syndrome information and guidance documents, management guidelines and protocols, templates for patient letters and family history taking and patient information on colorectal and endometrial cancers.

How should I use these documents?

There are a number of template documents on this page which contain information that can be used by any Trust across the East Midlands and East of England.

However, you will need to download the document(s) you wish to use and apply your own Trust template and branding, including logo and any local contact information. These documents are clearly marked out by the following image:

Templates bearing this image need to be put into your own NHS Trust templates/branding.

Testing guidance and protocols

Testing strategies for Lynch syndrome in people with endometrial cancer (NICE diagnostics guidance DG42)

Endometrial Cancer Lynch Syndrome Testing Protocol (CUH)

Management Guidelines

UK Cancer Genetics Group

The following management guidelines have been produced by the UK Cancer Genetics Group (opens in a new tab) (UKCGG).

St. Mark's and Lynch Syndrome UK

Aspirin and Lynch Syndrome - FAQs for People with Lynch Syndrome

Record of discussion form

LYNCH Record of discussion form v1 2023

Patient letter templates

These template letters are intended to help with reporting genetic results back to patients following testing for Lynch syndrome.

Letters for patients following testing of tumour tissue (somatic testing)

Tumour tissue does not suggest Lynch syndrome

Tumour tissue suggestive of Lynch syndrome

Letters for patients following genetic testing of healthy cells in a blood sample (germline testing)

Blood test - pathogenic variant identified

Blood test - variant of unknown significance

Blood test - no variant identified

Family History Form

Family History Form regarding a family history of cancer

Patient Information

Aspirin and Lynch Syndrome – Frequently Asked Questions (FAQ) for People with Lynch Syndrome

Information for patients with endometrial cancer

LYNCH Patient information leaflet - Colorectal Cancer v1 2023