East Genomics

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Service turnaround times

Below are our latest (January 2024) turn around times for our three laboratories. Figures are updated towards the end of the month for the previous month.

The laboratories aim to report all genomic tests within the NHS England genomic test reporting time guidelines. Please note that reporting times will vary depending on the test type and referral type.

Results from tests requested through East GLH will be delivered by e-mail to a designated email address, which you will need to include on the request form. It is preferable for us if you use an nhs.net account and you are advised to use a departmental, rather than an individual, account if possible.

Patient information is only secure when sent via email from one nhs.net account to another nhs.net account. As such, when sending laboratory reports across networks, these will be encrypted.

If you have not sent in samples to us before for any particular test, please do make contact with the Laboratory in advance to make sure we have the capacity to process your request. Please email us on cuh.geneticslaboratories@nhs.net

Rare Disease turnaround times

Figures show percentage of tests delivered within the NHSE standard
Clinical Urgency Example Tests NHSE Target TAT (Days) Nottingham Cambridge Leicester
Urgent - Ultra Rapid QF-PCR for rapid trisomy detection 3 73% 86% N/A
Urgent - Rapid Microarray / karyotypes for prenatal /urgent postnatal (e.g. neonatal referrals) 14 80% 88% 71%
Non-urgent - Standard Standard paediatric or fetal loss microarray 42 96% 14%* 74%
Non-urgent - Standard Postnatal-karyotyping (e.g. fertility or familial microarray follow-up) 42 92% 5%* 37%
Non-urgent - Standard PWS/AS and Fragile X 42 92% 99% N/A
Urgent - Rapid DPYD 5 N/A 99% N/A
Urgent - Rapid PCR based tests for predictive testing 14 33% 57% N/A
Non-urgent - Standard Rare disease single gene screening, known familial variant testing & standard STR based analysis 42 N/A 78% N/A
Non-urgent Standard Rare disease small panel testing (<10 genes) 42 87% 18%* N/A
Non-urgent - Complex standard Large gene panels (>10 genes), WES and WGS 84 13%* 13%* N/A

Please note, in order to reduce the backlog, some non-urgent standard and complex gene panels are outsourced to an external ISO15189 accredited laboratory (Medicover) for testing. Results are returned to the Cambridge laboratory and forwarded on to the referring clinician.

Haem-Onc turnaround times

Figures show percentage tests delivered within the NHSE standard
Clinical Urgency Example Tests NHSE Target TAT
(Days)
Nottingham Cambridge Leicester
Clinical Urgency Urgent – Ultra Rapid Example Tests Urgent haemato-oncology FISH/RT-PCR (e.g. BCR/ABL1, PML/RARA) NHSE Target TAT
(Days)
3
Nottingham 83% Cambridge 81% Leicester 100%
Clinical Urgency Urgent Example Tests Urgent diagnostic pathway/upfront treatment determining (FISH/clonality/targeted mutation/karyotype) NHSE Target TAT
(Days)
7
Nottingham 42% Cambridge 79% Leicester N/A
Clinical Urgency Urgent - Rapid Example Tests Urgent haemato-oncology karyotyping NHSE Target TAT
(Days)
14
Nottingham 71% Cambridge N/A Leicester 100%
Clinical Urgency Non-urgent - Standard Example Tests Routine array/karyotype NHSE Target TAT
(Days)
21
Nottingham 50% Cambridge 84% Leicester 78%
Clinical Urgency Non-urgent - Standard Example Tests Haemato-oncology FISH NHSE Target TAT
(Days)
21
Nottingham N/A Cambridge N/A Leicester 100%
Clinical Urgency Non-urgent - Standard Example Tests NGS panels for haemato-oncology referrals (Haem-Onc NGS panels) NHSE Target TAT
(Days)
21
Nottingham N/A Cambridge 8%* Leicester N/A

Solid Cancer turnaround times

Figures show percentage turnaround times within NHSE standard
Clinical Urgency Example Tests NHSE Target TAT
(Days)
Nottingham Cambridge Leicester
Urgent - Rapid Example Tests FISH for solid cancers NHSE Target TAT
(Days)
14
Nottingham 85% Cambridge 96% Leicester 100%
Urgent - Rapid Example Tests MGMT promoter methylation NHSE Target TAT
(Days)
14
Nottingham N/A Cambridge 100% Leicester N/A
Urgent - Rapid Example Tests BRAF NHSE Target TAT
(Days)
14
Nottingham 100% Cambridge N/A Leicester N/A
Urgent - Rapid Example Tests NGS - targeted DNA NHSE Target TAT
(Days)
21
Nottingham 10% Cambridge 98% Leicester 100%
Urgent - Rapid Example Tests NGS - targeted RNA NHSE Target TAT
(Days)
21
Nottingham N/A Cambridge 98% Leicester N/A
Urgent - Rapid Example Tests Pan cancer - DNA NHSE Target TAT
(Days)
21
Nottingham N/A Cambridge 57% Leicester N/A
Example Tests Pan cancer - RNA NHSE Target TAT
(Days)
21
Nottingham N/A Cambridge 55% Leicester N/A
Urgent - Rapid Example Tests FISH for solid cancers NHSE Target TAT
(Days)
21
Nottingham 63% Cambridge N/A Leicester N/A
Non-urgent Standard Example Tests MSI testing & MLH1 promoter methylation NHSE Target TAT
(Days)
42
Nottingham 0%* Cambridge 95% Leicester N/A

*denotes areas with backlog